I got through University running Debian testing. It was mostly fine, some Linux based subjects were way easier without dealing with a VM (they recommended against WSL for some reason).

However there were a couple units that absolutely required you to use Visual Studio (non-code), I occasionally used a VM, the Uni IT also provided me with a remote VM (there’s a form to fill and and it’s all automated). But I mostly used Rider, which for one unit it confused their CI and I got marked down for (otherwise got top marks so it’s fine).

For office, it didn’t matter. Group projects mostly used Google Docs, occasionally Microsoft Office where the online version worked fine. All my units wanted PDFs at the end anyway, so it does not matter that you used LibreOffice or whatever. Some units provided you with DOCX templates, I had no issues opening them with LibreOffice.

Edit: People are mentioning online exams, my Uni did ‘online quizzes’ which worked fine, and some had to be done in class on their PCs anyway. Final exams where always done on paper.